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L J Rubin Selected Research

Endothelin-1 (Endothelin 1)

10/2001Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study.

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L J Rubin Research Topics

Disease

12Pulmonary Hypertension
04/2004 - 01/2000
6Familial Primary Pulmonary Hypertension
06/2009 - 01/2000
4Pulmonary Arterial Hypertension
12/2006 - 01/2003
1Systemic Scleroderma (Systemic Sclerosis)
07/2010
1Interstitial Lung Diseases (Interstitial Lung Disease)
07/2010
1Clinical Deterioration
04/2004
1Pulmonary Veno-Occlusive Disease (Veno Occlusive Disease, Pulmonary)
01/2003
1Infections
09/2001
1Genetic Predisposition to Disease (Genetic Predisposition)
09/2001
1Disease Progression
09/2001
1Hypoxia (Hypoxemia)
04/2001
1Vascular Remodeling
11/2000
1Dyspnea (Shortness of Breath)
03/2000
1Nausea
03/2000
1Pain (Aches)
03/2000
1Pneumothorax
03/2000
1Hemorrhage
03/2000
1Fatigue
03/2000
1Raynaud Disease (Raynaud's Disease)
03/2000
1Cellulitis
03/2000
1Sepsis (Septicemia)
03/2000
1Anorexia
03/2000
1digital ulcers
03/2000
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2000

Drug/Important Bio-Agent (IBA)

5Bosentan (Tracleer)FDA Link
07/2010 - 10/2001
5Epoprostenol (Prostacyclin)FDA LinkGeneric
12/2005 - 01/2000
4Endothelin Receptor AntagonistsIBA
07/2010 - 10/2001
2Endothelins (Endothelin)IBA
07/2010 - 10/2001
2ProstaglandinsIBA
09/2004 - 11/2001
2Vasoconstrictor AgentsIBA
10/2001 - 09/2001
2Proteins (Proteins, Gene)FDA Link
09/2001 - 04/2001
1Vasodilator Agents (Vasodilators)IBA
06/2009
1treprostinilFDA Link
12/2006
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2003
1Endothelin-1 (Endothelin 1)IBA
10/2001
1MitogensIBA
10/2001
1A-factor (Streptomyces)IBA
07/2001
1Messenger RNA (mRNA)IBA
04/2001
1Appetite Depressants (Anorectics)IBA
11/2000
1ElementsIBA
11/2000
1AminorexIBA
11/2000
1Pharmaceutical PreparationsIBA
11/2000

Therapy/Procedure

8Therapeutics
07/2010 - 01/2000
1Endarterectomy (Thromboendarterectomy)
04/2004
1Postoperative Care
09/2001
1Investigational Therapies (Experimental Therapy)
09/2001